경성대학교 약학대학 임상약학연구실은 효율적인 신약개발과 합리적인 약물요법 설계를 위한 계량약리학 (pharmacometrics), 약물동태/약물동력학 모델링 (pharmacokinetic/pharmacodynamic modeling), 메타분석 (meta-analysis) 연구를 수행하고 있습니다.

In-hwan Baek, Ph.D. (백인환) 
Professor, College of Pharmacy, Kyungsung University 

학력
2001. 03 - 2005. 02  충남대학교 약학대학 약학과 (약학사)
2005. 03 - 2007. 02  충남대학교 대학원 약학과 (약학석사)
2007. 03 - 2011. 02  충남대학교 대학원 약학과 (약학박사) 

주요경력
2013. 09 - 현재  경성대학교 약학대학 교수
2021. 03 - 현재   호주 퀸즐랜드대학교 약학대학 명예교수
2010. 12 - 2013. 08  유한양행 중앙연구소 선임연구원 

주요연구분야

1. Population PK/PD modelling & simulation for clinical therapeutics.

2. Mechanism-based PK/PD modelling & simulation for drug development.

3. Interspecies PK modeling for estimation of human starting dose in first-in-human study using allometric scaling.

4. Systematic review & meta-analysis for pharmacotherapy

수행 중인 과제

- 한국연구재단 기본연구지원사업 (과제명: 비알콜성지방간염 치료제 개발을 위한 파네소이드 X 수용체 효능제의 계량약리 연구)

- 식품의약품안전처 위탁용역과제 (과제명: 의약품 설계기반 품질고도화(QbD) 제도 도입기반 구축)

- 제약회사 위탁용역과제

최근 3년, 2021~ 현재 

(‪In-hwan Baek‬ - ‪Google 학술 검색‬) 

2023

Hyejung Jang1, Nayoung Han, Christine E Staatz, Jae-Hwan Kwak, In-hwan Baek^†. Effect on Lipid Profile and Clinical Outcomes of Obeticholic Acid for the Treatment of Primary Biliary Cholangitis and Metabolic Dysfunction-Associated Steatohepatitis: A Systematic Review and Meta-Analysis. Clinics and Research in Hepatology and Gastroenterology, 47(10):102227 

Seon-Kwang Lee1, Eun-Sol Ha1, Heejun Park1, Ji-Su Jeong, Jeong-Soo Kim, In-hwan Baek, In-Soo Yoon, Hwayoung Yun, Jin-Wook Yoo, Hyung Ryong Moon, Min-Soo Kim†. Synergistic solvation effect and modeling of itraconazole solubility in eight binary mixtures (dichloromethane and chloroform+ primary alcohol) at the range of 288.15 K to 308.15 K. The Journal of Chemical Thermodynamics, 185:107115 

2022

Seoyeon Lee1, Christine E Staatz, Nayoung Han, In-hwan Baek^†. Safety evaluation of oral calcitonin-gene-related peptide receptor antagonists in patients with acute migraine: a systematic review and meta-analysis. European Journal of Clinical Pharmacology, 78(9):1365-1376 

Quyen Thi Tran1, In-hwan Baek¹, Na-Young Han, Hwi-Yeol Yun, Jung-Woo Chae. The Effect of CYP2D6 Phenotypes on the Pharmacokinetics of Propafenone: A Systematic Review and Meta-Analysis. Pharmaceutics, 14(7):1446 

Yoonjeong Kim1, Jiye Pyeon, In-hwan Baek, and Younghwa Kim^†. Development of Simultaneous Analytical Method for Five Lignans in Edible Seeds. The Korean Journal of Food and Nutrition. 35(6):543-551 

2021

Jae-Hwan Kwak1, Younghwa Kim1, Christine E. Staatz, In-hwan Baek^†. Oral bioavailability and pharmacokinetics of esculetin following intravenous and oral administration in rats. Xenobiotica, 51(7):811-817 

Min-Soo Kim1, In-hwan Baek^†. Pharmacokinetic analysis of two different doses of simvastatin following oral administration in dogs. Journal of Veterinary Pharmacology and Therapeutics, 44(3):333-341 

In‐hwan Baek^1,†, Hyun‐moon Back, Jung‐woo Chae, Eun‐Sol Ha, Heejun Park, Du Hyung Choi, Christine E. Staatz, Min‐Soo Kim. Pharmacokinetics of eperisone following oral administration in healthy Korean volunteers. Biopharmaceutics & Drug Disposition, 42(2-3):94-102 

Dong Kyoung Ha1, Min Ji Kim, Nayoung Han, Jae-Hwan Kwak†, In-hwan Baek^†. Comparative Efficacy of Oral Calcitonin-Gene–Related Peptide Antagonists for the Treatment of Acute Migraine: Updated Meta-analysis. Clinical Drug Investigation, 41(2):119-132 

Won-Ho Kang1, Jae-Yeon Lee, Jung-Woo Chae, Kyeong-Ryoon Lee, In-hwan Baek, Min-Soo Kim, Hyun-Moon Back, Sangkeun Jung, Craig Shaffer, Rada Savic, Hwi-Yeol Yun†. Population Pharmacokinetic Method to Predict Within-Subject Variability Using Single-Period Clinical Data. Pharmaceuticals, 14(2):114 

Dong Kyun Kim1, Soo Yong Chung, Jae-Hwan Kwak, Min-Soo Kim, Christine E Staatz, Hye Suk Lee, In-hwan Baek^†. Pharmacokinetic interaction between dronedarone and ticagrelor following oral administration in rats. Xenobiotica, 51(2):194-201 

Jong-Hwa Lee1, Dae Young Lee, Kyung Koo Kang, Eun Ju Jeong, Christine E Staatz, In-hwan Baek^†. Gender differences and dose proportionality in the toxicokinetics of udenafil and its active metabolite following oral administration in rodents. Toxicology and Applied Pharmacology, 410:115339 

Eun-Sol Ha1, Du Hyung Choi, In-hwan Baek, Heejun Park and Min-Soo Kim. Enhanced Oral Bioavailability of Resveratrol by Using Neutralized Eudragit E Solid Dispersion Prepared via Spray Drying. Antioxidants, 10(1):90 

지도교수 : 백인환 

(2024년 현재)
박사과정 : 정영란
학부연구생 :  오영훈, 정창현, 류수윤 

Contact :  baek@ks.ac.kr
Homepage :   https://cms2.ks.ac.kr/pharmacy/sub.do?mCode=MN0004&mode=view&idx=PS0010