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Biosens. Bioelectron., Available online 11 March 2025, 117372 | https://doi.org/10.1016/j.bios.2025.117372
Soft Imperceptible Wearable Electronics for At-Home Cardiovascular Monitoring of Infants with Single Ventricle Heart Disease
Lauren Zhou 1,2†, Alaa Aljiffry 3,4†, Yoon Jae Lee 2,5, Jared Matthews 1,2, Brooke Seitter 3, Ira Soltis 1,2, Yunuo Huang 6, Kevin Maher 3,4, Woon-Hong Yeo 1,2,7
1George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
2Wearable Intelligent Systems and Healthcare Center (WISH Center) at the Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA
3Division of Cardiology, Pediatric Cardiology, Children's Healthcare of Atlanta, Atlanta, GA 30322 USA
4Department of Pediatrics, Division of Pediatric Cardiology, Emory University School of Medicine, Atlanta, GA, USA
5School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA
6School of Industrial Design, Georgia Institute of Technology, Atlanta, GA, USA
7Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA, USA
†They contributed equally to this work.
Corresponding author : Woon-Hong Yeo
1George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
2Wearable Intelligent Systems and Healthcare Center (WISH Center) at the Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA
3Division of Cardiology, Pediatric Cardiology, Children's Healthcare of Atlanta, Atlanta, GA 30322 USA
4Department of Pediatrics, Division of Pediatric Cardiology, Emory University School of Medicine, Atlanta, GA, USA
5School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA
6School of Industrial Design, Georgia Institute of Technology, Atlanta, GA, USA
7Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA, USA
†They contributed equally to this work.
Corresponding author : Woon-Hong Yeo
Abstract
Patients with single ventricle heart disease (SVHD) require multiple palliative surgeries. Due to high mortality rates observed during the four to sixth-month interstage period between the first and second surgery, at-home monitoring practices are important. However, modern-day interstage monitoring does not offer comprehensive quantitative tracking of health conditions since it relies on logging the infant's weight, feeding patterns, and oxygen saturation once a day in a journal. Here, we introduce a soft wearable electronic device for the home monitoring of SVHD patients. The ultrathin, imperceptible, wireless system is designed for safe integration with infants' delicate skin. The system features a chest-mounted biopatch and forehead-mounted pulse oximeter, streaming real-time data to a cloud-based platform. This smart device has built-in alert functions to help caregivers recognize when the patients should be returned to the hospital for in-person observation, easing decision-making from non-clinically trained personnel. In addition, the patient-tailored database also improves the communication between the home and hospital, reducing the load on caretakers during this stressful period.
논문정보
- Research article
- 2025년 03월 (BRIC 등록일 2025-03-13)
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