Jihwan Yun, MD, PhD1; Daeun Shin, MD, MSc2; Eun Hye Lee, MD, PhD2; Jun Pyo Kim, MD, PhD2; Hongki Ham, MSc2,3,4,5; Yuna Gu, MSc2,6; Min Young Chun, MD, PhD7,8; Sung Hoon Kang, MD, PhD9; Hee Jin Kim, MD, PhD2,3,4,6; Duk L. Na, MD, PhD2,10; Chi-Hun Kim, MD, PhD11; Ko Woon Kim, MD, PhD12; Si Eun Kim, MD, PhD13; Yeshin Kim, MD, PhD14; Jaeho Kim, MD, PhD15; Na-Yeon Jung, MD, PhD16; Yeo Jin Kim, MD, PhD17; Soo Hyun Cho, MD, PhD18; Henrik Zetterberg, MD, PhD19,20,21,22,23,24; Kaj Blennow, MD, PhD19,20,25,26; Fernando Gonzalez-Ortiz, MD, MSc19,20; Nicholas J. Ashton, PhD19,27,28,29; Joseph Therriault, PhD30,31; Nesrine Rahmouni, MSc30,31; Pedro Rosa-Neto, MD, PhD30,31,32,33; Michael W. Weiner, MD, PhD33; Sang Won Seo, MD, PhD2,3,4,5,6; Hyemin Jang, MD, PhD34; for the ADNI, TRIAD, and K-ROAD study groups
1Department of Neurology, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea
2Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
3Alzheimer’s Disease Convergence Research Center, Samsung Medical Center, Seoul, South Korea
4Department of Digital Health, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University. Seoul, South Korea
5Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Suwon, South Korea
6Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, South Korea
7Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea
8Department of Neurology, Yongin Severance Hospital, Yonsei University Health System, Yongin, South Korea
9Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, South Korea
10Happymid Clinic, Seoul, South Korea
11Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, South Korea
12Department of Neurology, Jeonbuk National University Medical School and Hospital, Jeonju, Korea
13Department of Neurology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea
14Department of Neurology, Kangdong Sacred Heart Hospital, Seoul, Republic of Korea
15Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea
16Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
17Department of Neurology, Kangwon National University College of Medicine, Chuncheon-si, Korea
18Department of Neurology, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, Korea
19Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
20Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden
21Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, United Kingdom
22UK Dementia Research Institute at UCL, London, United Kingdom
23Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China
24Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792
25Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France
26Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, People’s Republic of China
27King’s College London, Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, United Kingdom
28NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation, London, United Kingdom
29Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway
30McGill University Research Centre for Studies in Aging, Alzheimer’s Disease Research Unit, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux de l’Ouest-de-l’Île-de-Montréal
31Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
32Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania
33Department of Radiology and Biomedical Imaging, University of California, San Francisco
34Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea
Corresponding authors : Hyemin Jang, MD, PhD, Sang Won Seo, MD, PhD