Siyu Sun,1,18,* Eunae You,2,18 Jungeui Hong,3,4 David Hoyos,5 Isabella S. Del Priore,6 Kaloyan M. Tsanov,7 Om Mattagajasingh,8 Andrea Di Gioacchino,9 Sajid A. Marhon,10 Jonathan Chacon-Barahona,5 Hao Li,1 Hua Jiang,11 Samira Hozeifi,12 Omar Rosas-Bringas,12 Katherine H. Xu,2 Yuhui Song,2 Evan R. Lang,2 Alexandra S. Rojas,2 Linda T. Nieman,2 Bidish K. Patel,2 Rajmohan Murali,13 Pharto Chanda,13 Ali Karacay,13 Nicolas Vabret,15 Daniel D. De Carvalho,10,14 Daniel Zenklusen,8 John LaCava,10,11,19 Scott W. Lowe,7,16,19 David T. Ting,2,19 Christine A. Iacobuzio-Donahue,3,4,13,19 Alexander Solovyov,1,19 and Benjamin D. Greenbaum 1,17,19,20,*
1Halvorsen Center for Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
2Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA
3David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA
4Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
5Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY, USA
6Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA
7Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
8Department of Biochemistry and Molecular Medicine, Universite´ de Montre´ al, Montreal, QC, Canada
9Laboratoire de Physique de l’Ecole Normale Supe´rieure, Sorbonne Universite´ , Universite´ de Paris, Paris, France
10Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
11Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA
12European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands
13Last Wish Program and Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
14Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
15Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai, New York, NY, USA
16Howard Hughes Medical Institute, Chevy Chase, MD, USA
17Physiology, Biophysics & Systems Biology, Weill Cornell Medicine, New York, NY, USA
18These authors contributed equally
19Senior author
20Lead contact
*Corresponding authors: correspondence to Siyu Sun or Benjamin D. Greenbaum