김희훈 (Yale School of Medicine)

한빛사논문

조회240

Yale School of Medicine

CV File 311 kb

Cell Metab., Volume 36, Issue 9 , 3 Sep. 2024, Pages 1911-1913 | https://doi.org/10.1016/j.cmet.2024.08.003 [Spotlight] Defying "IL-11ness" by inhibiting inflammation: Strategy for health and longevity

Hee-Hoon Kim ^1,2, Vishwa Deep Dixit ^1,2,3

¹Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA

²Department of Immunobiology and Comparative Medicine, Yale School of Medicine, New Haven, CT 06520, USA

³Yale Center for Research on Aging, New Haven, CT 06520, USA

Corresponding author: Vishwa Deep Dixit

Abstract

Organismal aging involves several hallmark pathways, including chronic inflammation and metabolic dysfunction. However, the origin of age-related inflammation is incompletely understood. In a recent study published in Nature,1 Widjaja et al. show that blocking the age-related increase in IL-11 restores immune-metabolic homeostasis and extends healthspan and lifespan in mice.

논문정보

형식Spotlight
게재일2024년 09월 (BRIC 등록일 2024-09-04)
연구진국외 연구진
분야 생명과학 > 노화/암생물학

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