한빛사논문
- 조회253
Jae-Young Bae1,16, Gyeong-Seok Hwang 2,16, Young-Seo Kim1,16, Jooik Jeon3, Minseong Chae1,4, Joon-Woo Kim5, Sian Lee6,7, Seongchan Kim6,8,9, Soo-Hwan Lee6, Sung-Geun Choi1, Ju-Yong Lee1, Jae-Hwan Lee1, Kyung-Sub Kim1, Joo-Hyeon Park1, Woo-Jin Lee1, Yu-Chan Kim6,10, Kang-Sik Lee4, Jeonghyun Kim5, Hyojin Lee6,11, Jung Keun Hyun3,12,13, Ju-Young Kim2 & Seung-Kyun Kang1,14,15
1Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea.
2Department of Materials Science and Engineering, UNIST (Ulsan National Institute of Science and Technology), Ulsan, Republic of Korea.
3Department of Nanobiomedical Science and BK21 NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of Korea.
4Biomedical Engineering Research Center, Asan Institute for Life Sciences, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Republic of Korea.
5Department of Electronic Convergence Engineering, Kwangwoon University, Seoul, Republic of Korea.
6Biomaterials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
7School of Biomedical Engineering, Korea University, Seoul, Republic of Korea.
8Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
9College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
10Division of Bio-Medical Science & Technology, KIST School – Korea University of Science and Technology (UST), Seoul, Republic of Korea.
11KIST-SKKU Brain Research Center, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea.
12Department of Rehabilitation Medicine, College of Medicine, Dankook University, Cheonan, Republic of Korea.
13Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
14Research Institute of Advanced Materials (RIAM), Seoul National University, Seoul, Republic of Korea.
15Nano Systems Institute SOFT Foundry, Seoul National University, Seoul, Republic of Korea.
16These authors contributed equally: Jae-Young Bae, Gyeong-Seok Hwang, Young-Seo Kim.
Corresponding authors
Correspondence to Jung Keun Hyun, Ju-Young Kim or Seung-Kyun Kang.
Abstract
High-density, large-area electronic interfaces are a key component of brain–computer interface technologies. However, current designs typically require patients to undergo invasive procedures, which can lead to various complications. Here, we report a biodegradable and self-deployable tent electrode for brain cortex interfacing. The system can be integrated with multiplexing arrays and a wireless module for near-field communication and data transfer. It can be programmably packaged and self-deployed using a syringe for minimally invasive delivery through a small hole. Following delivery, it can expand to cover an area around 200 times its initial size. The electrode also naturally decomposes within the body after use, minimizing the impact of subsequent removal surgery. Through in vivo demonstrations, we show that our cortical-interfacing platform can be used to stimulate large populations of cortical activities.
논문정보
- Research article
- 2024년 08월 (BRIC 등록일 2024-08-08)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 바이오소재
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