한빛사논문
- 조회30
전남대학교
Lei Wang1, Nomin-Erdene Oyunbaatar1, Yun-Jin Jeong2, Heonzoo Lee3, Yonggwan Won3, In-Seok Jeong4, Mukhammad Kayumov4, Francis O. Obiweluozor5, Dong-Su Kim6, Dong-Weon Lee1,7,8
1MEMS and Nanotechnology Laboratory, School of Mechanical Engineering, Chonnam National University, Gwangju, 61186 Republic of Korea
2Department of Automatic Systems, Chosun College of Science & Technology, Gwangju, 61453 Republic of Korea
3Department of Intelligent Electronics and Computer Engineering, Chonnam National University, Gwangju, 61186 Republic of Korea
4Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hospital and Medical School, Gwangju, 61469 Republic of Korea
5Research and Business Development Foundation, Chonnam National University, Gwangju, 61186 Republic of Korea
6Energy & Nano Technology Group, Korea Institute of Industrial Technology (KITECH), Gwangju, 61012 Republic of Korea
7Advanced Medical Device Research Center for Cardiovascular Disease, Chonnam National University, Gwangju, 61186 Republic of Korea
8Center for Next-Generation Sensor Research and Development, Chonnam National University, Gwangju, 61186 Republic of Korea
Corresponding Author : Dong-Weon Lee
Abstract
To address the complication of in-stent restenosis that occurs with traditional stent treatments, this study proposes an innovative hybrid smart stent-based medical system. This approach allows to overcome the limitations of existing bare metal or polymer-based smart stents, which interfere with radio frequency signals, less deformability, or do not provide adequate radial support, respectively. The proposed hybrid stent, which uses a Co/Cr–polycaprolactone (PCL)–Co/Cr configuration connected by a unique dual inverted Y-type connector for metal–polymer integration is integrated with a LC wireless pressure sensor fabricated through a semiconductor process. The fabricated hybrid stent made by laser machining and custom-made 3D printing, offers excellent properties such as radial strength (0.125 N/mm) and flexibility (2 N mm2) and provides intravascular information to the outside through the integrated sensor without signal degradation. After basic experiments using a phantom, animal experiments are conducted by combining the fabricated sensor with artificial blood vessel, and the results measured by the external antenna system are consistent with the results of a commercial reference sensor. The proposed wireless sensor-based smart stents and artificial blood vessels aim to gather diverse patient health data for integration with artificial intelligence, laying the groundwork for next-generation medical innovation.
논문정보
- Research article
- 2024년 08월 (BRIC 등록일 2024-09-12)
- 국내 연구진
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