Steve Park (KAIST)

한빛사논문

조회117

KAIST

Nat. Commun., Jul 11 2024, 15 (1) 5839 | https://doi.org/10.1038/s41467-024-50264-6 3D printable and biocompatible PEDOT:PSS-ionic liquid colloids with high conductivity for rapid on-demand fabrication of 3D bioelectronics

Byungkook Oh^1,9, Seunghyeok Baek^1,9, Kum Seok Nam^2,9, Changhoon Sung², Congqi Yang², Young-Soo Lim³, Min Sang Ju⁴, Soomin Kim¹, Taek-Soo Kim⁴, Sung-Min Park^3,5,6,7, Seongjun Park^1,2,8 & Steve Park^1,8

¹Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea.

²Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea.

³Department of Convergence IT Engineering (CiTE), Pohang University of Science and Technology (POSTECH), 77 Cheongamro, Nam-gu, Pohang-si, Gyeongsangbuk-do, Republic of Korea.

⁴Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology(KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea.

⁵Department of Electrical Engineering, Pohang University of Science and Technology(POSTECH), 77 Cheongam-ro, Nam-gu, Pohang-si, Gyeongsangbuk-do, Republic of Korea.

⁶Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang-si, Gyeongsangbuk-do, Republic of Korea.

⁷Institute of Convergence Science, Yonsei University, Seoul, Republic of Korea.

⁸KAIST Institute for NanoCentury, 291 Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea.

⁹These authors contributed equally: Byungkook Oh, Seunghyeok Baek, Kum Seok Nam.

Corresponding authors

Correspondence to Seongjun Park or Steve Park.

Abstract

3D printing has been widely used for on-demand prototyping of complex three-dimensional structures. In biomedical applications, PEDOT:PSS has emerged as a promising material in versatile bioelectronics due to its tissue-like mechanical properties and suitable electrical properties. However, previously developed PEDOT:PSS inks have not been able to fully utilize the advantages of commercial 3D printing due to its long post treatment times, difficulty in high aspect ratio printing, and low conductivity. We propose a one-shot strategy for the fabrication of PEDOT:PSS ink that is able to simultaneously achieve on-demand biocompatibility (no post treatment), structural integrity during 3D printing for tall three-dimensional structures, and high conductivity for rapid-prototyping. By using ionic liquid-facilitated PEDOT:PSS colloidal stacking induced by a centrifugal protocol, a viscoplastic PEDOT:PSS-ionic liquid colloidal (PILC) ink was developed. PILC inks exhibit high-aspect ratio vertical stacking, omnidirectional printability for generating suspended architectures, high conductivity (~286 S/cm), and high-resolution printing (~50 µm). We demonstrate the on-demand and versatile applicability of PILC inks through the fabrication of 3D circuit boards, on-skin physiological signal monitoring e-tattoos, and implantable bioelectronics (opto-electrocorticography recording, low voltage sciatic nerve stimulation and recording from deeper brain layers via 3D vertical spike arrays).

논문정보

형식Research article
게재일2024년 07월 (BRIC 등록일 2024-08-07)
연구진국내 연구진
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