이홍균 (Harvard Medical School, Brigham and Women's Hospital)

한빛사논문

조회329

Harvard Medical School, Brigham and Women's Hospital

CV File 254 kb

Mol. Cell, VOLUME 84, ISSUE 14, P2596-2597, JULY 25, 2024 | https://doi.org/10.1016/j.molcel.2024.06.034 [SPOTLIGHT] STING: Stay near to STIM(1) neuroprotection

Hong-Gyun Lee ¹ and Francisco J. Quintana ^1,2,3,*

¹Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
²Broad Institute of MIT and Harvard, Cambridge, MA, USA
³Gene Lay Institute of Immunology and Inflammation, Boston, MA, USA

^*Corresponding author: correspondence to Francisco J. Quintana

Abstract

In a recent publication in Cell, Woo et al. report that stimulator of interferon genes (STING) links inflammation with glutamate-driven excitotoxicity to induce ferroptosis, identifying a mechanism of inflammation-induced neurodegeneration and also a novel candidate therapeutic target for multiple sclerosis.

논문정보

형식SPOTLIGHT
게재일2024년 07월 (BRIC 등록일 2024-07-26)
연구진국외 연구진
분야 의약학 > 신경의학

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