한빛사
>
한빛사논문
한빛사논문
- 조회224
Carbohydr. Polym., Available online 23 May 2024 | https://doi.org/10.1016/j.carbpol.2024.122311
Engineered inulin-based hybrid biomaterials for augmented immunomodulatory responses
Ashok Kumar Jangid, Kyung Mu Noh, Sungjun Kim, Kyobum Kim
Department of Chemical & Biochemical Engineering, Dongguk University, Seoul 04620, Republic of Korea
Corresponding author : Kyobum Kim
Abstract
Modified biopolymers that are based on prebiotics have been found to significantly contribute to immunomodulatory events. In recent years, there has been a growing use of modified biomaterials and polymer-functionalized nanomaterials in the treatment of various tumors by activating immune cells. However, the effectiveness of immune cells against tumors is hindered by several biological barriers, which highlights the importance of harnessing prebiotic-based biopolymers to enhance host defenses against cancer, thus advancing cancer prevention strategies. Inulin, in particular, plays a crucial role in activating immune cells and promoting the secretion of cytokines. Therefore, this mini-review aims to emphasize the importance of inulin in immunomodulatory responses, the development of inulin-based hybrid biopolymers, and the role of inulin in enhancing immunity and modifying cell surfaces. Furthermore, we discuss the various approaches of chemical modification for inulin and their potential use in cancer treatment, particularly in the field of cancer immunotherapy.
논문정보
- Review Paper
- 2024년 05월 (BRIC 등록일 2024-06-11)
- 국내 연구진
- 생명과학 > 생물공학
댓글 작성 로그인
팝업 닫기관련 링크
연구자 키워드
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
해당논문 저자보기
