김진희 (세종대학교)

한빛사논문

조회119

김진희Jin Hee Kim

세종대학교

Ageing Res. Rev., May 18 2024, S1568-1637(24)00162-4 | https://doi.org/10.1016/j.arr.2024.102344 Hypertension in an Ageing Population: Diagnosis, Mechanisms, Collateral Health Risks, Treatments, and Clinical Challenges

Jin Hee Kim, Rekha Thiruvengadam

Department of Integrative Bioscience & Biotechnology, Sejong University, Seoul 05006, Republic of Korea

Correspondence to: Jin Hee Kim

Abstract

Ageing population is considerably increasing worldwide, which is considered to reflect an improved quality of life. However, longevity in the human lifespan has increased the burden of late-life illnesses including cancer, neurodegeneration, and cardiovascular dysfunction. Of these, hypertension is the most common condition with huge health risks, with an increased prevalence among the elderly. In this review, we outline the current guidelines for defining hypertension and examine the detailed mechanisms underlying the relationship between hypertension and ageing-related outcomes, including sodium sensitivity, arterial stiffness, endothelial dysfunction, isolated systolic hypertension, white coat effect, and orthostatic hypertension. As hypertension-related collateral health risk increases among the elderly, the available management strategies are necessary to overcome the clinical treatment challenges faced among elderly population. To improve longevity and reduce adverse health effects, potential approaches producing crucial information into new era of medicine should be considered in the prevention and treatment of hypertension among elderly population. This review provides an overview of mechanisms underlying hypertension and its related collateral health risk in elderly population, along with multiple approaches and management strategies to improve the clinical challenges among elderly population.

논문정보

형식Review Paper
게재일2024년 05월 (BRIC 등록일 2024-06-11)
연구진국내 연구진
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