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Trends Endocrinol. Metab., May 16 2024, S1043-2760(24)00121-8 | https://doi.org/10.1016/j.tem.2024.05.003
[Spotlight] The sphinx helps to answer the riddle of cardiac regeneration
Jae Woo Jung 1, Timothy Hla 2, Zoltan Arany 1
1Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
2Vascular Biology Program, Boston Children's Hospital and Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
Correspondence: Zoltan Arany
Abstract
Cardiomyocyte (CM) death drives heart failure worldwide, and efficient CM regeneration remains a fervently pursued but unachieved goal. Ji and colleagues recently described a novel approach to regeneration by orchestrating divergent sphingolipid signaling pathways in CMs and cardiac fibroblasts (CFs). The findings uncover new biology and offer interesting translational opportunities.
논문정보
- Spotlight
- 2024년 05월 (BRIC 등록일 2024-05-21)
- 국외 연구진
- 생명과학 > 세포생물학
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