한빛사논문
- 조회290
Wang-Soo Lee 1, E. Dale Abel 2*, Jaetaek Kim 3*
1Chung-Ang University, Seoul, Korea (South).
2Department of Medicine, David Geffen School of Medicine and UCLA Health, Los Angeles, CA, United States.
3Division of Endocrinology and Metabolism, Department of Internal Medicine, Chung-Ang University, Seoul, Korea (South).
*Corresponding Authors: E. Dale Abel, Jaetaek Kim
Abstract
Insulin-like growth factor (IGF)-1 signaling has multiple physiological roles in cellular growth, metabolism, and aging. Myocardial hypertrophy, cell death, senescence, fibrosis, and electrical remodeling are hallmarks of various heart disease and contributes to the progression of heart failure. This review highlights the critical role of IGF-1 and its cognate receptor in cardiac hypertrophy, aging and remodeling.
논문정보
- Review Paper
- 2024년 05월 (BRIC 등록일 2024-05-08)
- 국내(교신)+국외 연구진
- 의약학 > 응용의학
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