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한빛사논문
한빛사논문
- 조회316
Exp. Mol. Med., May 01 2024, | https://doi.org/10.1038/s12276-024-01219-w
Neutrophils and neutrophil extracellular traps in oral health and disease
Tae Sung Kim1 and Niki M. Moutsopoulos1
1Oral Immunity and Infection Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
Corresponding author : Tae Sung Kim
Abstract
Neutrophils perform essential functions in antimicrobial defense and tissue maintenance at mucosal barriers. However, a dysregulated neutrophil response and, in particular, the excessive release of neutrophil extracellular traps (NETs) are implicated in the pathology of various diseases. In this review, we provide an overview of the basic concepts related to neutrophil functions, including NET formation, and discuss the mechanisms associated with NET activation and function in the context of the prevalent oral disease periodontitis.
논문정보
- Review Paper
- 2024년 05월 (BRIC 등록일 2024-05-03)
- 국외 연구진
- 생명과학 > 면역학
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