류승화 (KAIST)

한빛사논문

조회196

류승화Seunghwa Ryu

KAIST

Adv. Mater., Mar 15 2024, | https://doi.org/10.1002/adma.202314374 On-demand Crack Formation on DNA Film via Organic Solvent-induced Dehydration

Soeun Lee ¹, Hyeonbin Moon², Juri Kim ¹, Seunghwa Ryu ², Soon Mo Park ^3,4, Dong Ki Yoon¹

¹Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.

²Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.

³Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.

⁴Department of Chemical and Biomolecular Engineering, Cornell University, Ithaca, 14853, USA.

CORRESPONDING AUTHORS : Seunghwa Ryu, Soon Mo Park, Dong Ki Yoon

Abstract

Crack is found on the soil when severe drought comes, which inspired the idea to rationalize patterning applications using dried deoxyribonucleic acid (DNA) film. DNA is one of the massively produced biomaterials in nature, showing the lyotropic liquid crystal (LC) phase in highly concentrated conditions. DNA nanostructures in the hydrated condition can be orientation controlled, which can be extended to make drying-induced cracks. We explore the controlled crack generation in oriented DNA films by inducing mechanical fracture through organic solvent-induced dehydration (OSID) using tetrahydrofuran (THF). The corresponding simulations show a strong correlation between the long axis of DNA due to the shrinkage during the dehydration and the direction of crack propagation. The cracks are controlled by simple brushing and a 3D printing method. This facile way of aligning cracks will be used in potential patterning applications. This article is protected by copyright. All rights reserved.

논문정보

형식Research article
게재일2024년 03월 (BRIC 등록일 2024-04-05)
연구진국내(교신)+국외 연구진
분야 바이오·의료융합 > 바이오소재

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