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J. Exp. Bot., Jan 27 2024, erae029 | https://doi.org/10.1093/jxb/erae029 ABI2 promotes flowering by inhibiting OST1/ABI5-dependent FLC activation in Arabidopsis

Akhtar Ali^1,2,6,*, Shah Zareen^3,6, Junghoon Park^1,6, Haris Ali Khan^3,6, Chae Jin Lim¹, Zein Eddin Bader³, Shah Hussain⁴, Woo Sik Chung⁴, Tsanko Gechev², Jose M. Pardo5, Dae-Jin Yun^3,*

¹Institute of Glocal Disease Control, Konkuk University, Seoul 05029, South Korea.

²Department Molecular Stress Physiology, Center of Plant Systems Biology and Biotechnology, Plovdiv 4000, Bulgaria,

³Department of Biomedical Science & Engineering, Konkuk University, Seoul 05029, South Korea.

⁴Division of Applied Life Science, Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju 660-701, South Korea.

⁵Instituto de Bioquímica Vegetaly Fotosíntesis, cicCartuja, CSICUniversidad de Sevilla, Americo Vespucio 49, Sevilla-41092, Spain.

⁶These authors equally contributed to this work.

Akhtar Ali, Shah Zareen, Junghoon Park and Haris Ali Khan equally contributed to this work.

^*Corresponding Authors : Prof. Dae-Jin Yun, Akhtar Ali

Abstract

The plant hormone abscisic acid (ABA) is an important regulator of plant growth and development and plays a crucial role in both biotic and abiotic stress responses. ABA modulates flowering time but the precise molecular mechanism remains poorly understood. Here we report ABA INSENSITIVE 2 (ABI2), as the only phosphatase from ABA-signaling core that positively regulates the transition to flowering in Arabidopsis. Loss-of-function abi2-2 mutant shows significantly delayed flowering both under long day (LD) and short day (SD) conditions. Expression of floral repressor genes such as FLOWERING LOCUS C (FLC) and CYCLING DOF FACTOR 1 (CDF1) was significantly up-regulated in abi2-2 plants while that of the flowering promoting genes FLOWERING LOCUS T (FT) and SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) was down-regulated. Through genetic interactions we further found that ost1-3 and abi5-1 mutations are epistatic to abi2-2, as both of them individually rescued the late flowering phenotype of abi2-2. Interestingly, ABA INSENSITIVE 5 (ABI5) phosphorylation and protein stability were enhanced in abi2-2 plants suggesting that ABI2 dephosphorylates ABI5, thereby reducing protein stability and the capacity to induce FLC expression. Our findings therefore uncovered the unexpected role of ABI2 to promote flowering by inhibiting ABI5-mediated FLC activation in Arabidopsis.

논문정보

형식Research article
게재일2024년 01월 (BRIC 등록일 2024-01-29)
연구진국내(교신)+국외 연구진
분야 생명과학 > 식물학

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