한빛사논문
- 조회388
Dong Ha Lee 1,2, Sunyoung Lim 1,3, Sung Soo Kwak 1, Joohee Kim 1
1Center for Bionics of Biomedical Research Division, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
2Department of Materials Science and Engineering, Yonsei University, Seoul, 03722, Republic of Korea.
3School of Biomedical Engineering, Korea University, Seoul, 02841, Republic of Korea.
D. H. Lee and S. Lim contributed equally to this work.
Corresponding authors: Sung Soo Kwak, Joohee Kim
Abstract
Skin-mediated drug delivery methods currently are receiving significant attention as a promising approach for the enhanced delivery of drugs through the skin. Skin-mediated drug delivery offers the potential to overcome the limitations of traditional drug delivery methods, including oral administration and intravenous injection. The challenges associated with drug permeation through layers of skin, which act as a major barrier, are explored, and strategies to overcome these limitations are discussed in detail. This review categorizes skin-mediated drug delivery methods based on the means of increasing drug permeation, and it provides a comprehensive overview of the mechanisms and techniques associated with these methods. In addition, recent advancements in the application of skin-mediated drug delivery are presented. The review also outlines the limitations of ongoing research and suggests future perspectives of studies regarding the skin-mediated delivery of drugs.
논문정보
- Review Paper
- 2023년 11월 (BRIC 등록일 2023-12-05)
- 국내 연구진
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