상위피인용논문
- 조회344
Jihoon Kim,a Gurusamy Saravanakumar,a Hyung Woo Choi,a Dongsik Parka and Won Jong Kim*a
aCenter for Self-assembly and Complexity, Institute for Basic Science Department of Chemistry, Pohang University of Science and Technology, Pohang 790-784, Korea
*Corresponding author: correspondence to Won Jong Kim
Abstract
Nitric oxide (NO) is one of the structurally smallest pharmaceutical molecules, which shows great potential as an anti-restenosis, wound healing, anticancer, and antibacterial agent. To date, while most of the studies have focused mainly on demonstrating the versatility of the NO-releasing materials, little effort has been made on developing successful NO-delivery strategies for advancing NO-mediated therapy. Thus, the quest for a rationally designed NO-delivery system is becoming one of the important issues in the biomedical applications of NO. This feature article discusses the overall research trends in the NO-delivery, focusing mainly on the various particle-type and coating platforms. The objective of this article is not only to highlight the fundamental principle and challenges associated with NO-delivery, but also to provide insight for the further development of novel NO-delivery platforms for clinical applications in the near future.
논문정보
- Review Paper
- 2014년 01월 (BRIC 등록일 2023-11-20)
- 국내 연구진
- 바이오·의료융합 > 바이오소재
- 120회 이상 인용된 논문
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