임미영 (한국식품연구원) | 한빛사논문 > 한빛사

한빛사논문

조회669

임미영Mi Young Lim

한국식품연구원

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Gut Microbes, Dec 2023, 15 (2) | https://doi.org/10.1080/19490976.2023.2278225 Gut microbiome in healthy aging versus those associated with frailty

Mi Young Lim ¹, Young-Do Nam ^{1 *}

¹Personalized Diet Research Group, Korea Food Research Institute, Jeollabuk-do, Republic of Korea.

^*Corresponding author: correspondence to Young-Do Nam

Abstract

As the proportion of older people in the world's population steadily increases, there is an urgent need to identify ways to support healthy aging. The gut microbiome has been proposed to be involved in aging-related diseases and has become an attractive target for improving health in older people. Herein, we cover the relationship between the gut microbiome and chronological age in adults, and then, we discuss the gut microbiome features associated with frailty, as a hallmark of unhealthy aging in older people. Furthermore, we describe the effects of microbiome-targeted interventions, such as dietary patterns and consumption of probiotics, prebiotics, and synbiotics, on modulating the gut microbiome composition and further promoting healthy aging. Further studies are needed to explore the underlying mechanisms of gut microbiome-induced aging complications and to develop personalized microbiome-based strategies for reducing the severity of frailty or preventing the onset of frailty in older adults.

논문정보

형식Review Paper
게재일2023년 12월 (BRIC 등록일 2023-11-17)
연구진국내 연구진
분야 생명과학 > 미생물학

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