정현호 (연세대학교 의과대학)

한빛사논문

조회286

연세대학교 의과대학

Adv. Healthc. Mater., Oct 11 2023, | https://doi.org/10.1002/adhm.202301753 Laser-Assisted Structuring of Graphene Films with Biocompatible Liquid Crystal Polymer for Skin/Brain-Interfaced Electrodes

Rowoon Park ¹, Dong Hyeon Lee ², Chin Su Koh ³, Young Woo Kwon ⁴, Seon Yeong Chae ⁴, Chang-Seok Kim ^1,4, Hyun Ho Jung ³, Joonsoo Jeong ⁵, Suck Won Hong^1,4

¹Department of Optics and Mechatronics Engineering, Department of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan, 46241, Republic of Korea.

²School of Mechanical Engineering, Pusan National University, Busan, 46241, Republic of Korea.

³Department of Neurosurgery, College of Medicine, Yonsei University, Seoul, 03722, Republic of Korea.

⁴Engineering Research Center for Color-Modulated Extra-Sensory Perception Technology, Pusan National University, Busan, 46241, Republic of Korea.

⁵School of Biomedical Convergence Engineering, Department of Information Convergence Engineering, Pusan National University, Yangsan, 50612, Republic of Korea.

R.P., D.H.L., and C.S.K. contributed equally to this work.

CORRESPONDING AUTHORS : Hyun Ho Jung, Joonsoo Jeong, Suck Won Hong

Abstract

The work presented here introduces a facile strategy for the development of flexible and stretchable electrodes that harness the robust characteristics of carbon nanomaterials through laser processing techniques on a liquid crystal polymer (LCP) film. By utilizing LCP film as a biocompatible electronic substrate, control is demonstrated over the laser irradiation parameters to achieve efficient pattern generation and transfer printing processes, thereby yielding highly conductive laser-induced graphene (LIG) bioelectrodes. To enhance the resolution of the patterned LIG film, shadow masks are employed during laser scanning on the LCP film surface. This approach is compatible with surface-mounted device integration, enabling the circuit writing of LIG/LCP materials in a flexible format. Moreover, kirigami-inspired on-skin bioelectrodes are introduced that exhibit reasonable stretchability, enabling independent connections to healthcare hardware platforms for electrocardiogram (ECG) and electromyography (EMG) measurements. Additionally, a brain-interfaced LIG microelectrode array is proposed that combines mechanically compliant architectures with LCP encapsulation for stimulation and recording purposes, leveraging their advantageous structural features and superior electrochemical properties. This developed approach offers a cost-effective and scalable route for producing patterned arrays of laser-converted graphene as bioelectrodes. These bioelectrodes serve as ideal circuit-enabled flexible substrates with long-term reliability in the ionic environment of the human body.

논문정보

형식Research article
게재일2023년 10월 (BRIC 등록일 2024-01-04)
연구진국내 연구진
분야 바이오·의료융합 > 바이오소재

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