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Sci. Data, Nov 03 2023, 10 (1) 761 | https://doi.org/10.1038/s41597-023-02661-7
A chromosome-level genome assembly of the Korean crossbred pig Nanchukmacdon (Sus scrofa)
Daehong Kwon1, Nayoung Park1, SuyeonWy1, Daehwan Lee1, Han-HaChai2, InCheol Cho3, Jongin Lee1, Kisang Kwon1, Heesun Kim1, Youngbeen Moon1, Juyeon Kim1, Woncheoul Park2 & Jaebum Kim1
1Department of Biomedical Science and Engineering, Konkuk University, Seoul, 05029, Republic of Korea.
2Animal Genomics and Bioinformatics Division, National Institute of Animal Science, RDA, Wanju, 55365, Republic of Korea.
3Subtropical Livestock Research Institute, National Institute of Animal Science, RDA, Jeju, 63242, Republic of Korea.
Corresponding authors : Correspondence to Woncheoul Park or Jaebum Kim.
Abstract
As plentiful high-quality genome assemblies have been accumulated, reference-guided genome assembly can be a good approach to reconstruct a high-quality assembly. Here, we present a chromosome-level genome assembly of the Korean crossbred pig called Nanchukmacdon (the NCMD assembly) using the reference-guided assembly approach with short and long reads. The NCMD assembly contains 20 chromosome-level scaffolds with a total size of 2.38 Gbp (N50: 138.77 Mbp). Its BUSCO score is 93.1%, which is comparable to the pig reference assembly, and a total of 20,588 protein-coding genes, 8,651 non-coding genes, and 996.14 Mbp of repetitive elements are annotated. The NCMD assembly was also used to close many gaps in the pig reference assembly. This NCMD assembly and annotation provide foundational resources for the genomic analyses of pig and related species.
논문정보
- Research article
- 2023년 11월 (BRIC 등록일 2023-11-06)
- 국내 연구진
- 생명과학 > 유전자발현
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