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민기윤Kiyoon Min

광주과학기술원

Adv. Drug Deliv. Rev., Available online 28 October 2023 | https://doi.org/10.1016/j.addr.2023.115119 Emerging drug delivery systems with traditional routes - A roadmap to chronic inflammatory diseases

Kiyoon Min ^a, Abhishek Sahu ^b, Sae Hyun Jeon ^a, Giyoong Tae ^a

^aSchool of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea

^bDepartment of Biotechnology, National Institute of Pharmaceutical Education & Research (NIPER), Hajipur, 844102, India

Corresponding author : Giyoong Tae

Abstract

Inflammation is prevalent and inevitable in daily life but can generally be accommodated by the immune systems. However, incapable self-healing and persistent inflammation can progress to chronic inflammation, leading to prevalent or fatal chronic diseases. This review comprehensively covers the topic of emerging drug delivery systems (DDSs) for the treatment of chronic inflammatory diseases (CIDs). First, we introduce the basic biology of the chronic inflammatory process and provide an overview of the main CIDs of the major organs. Next, up-to-date information on various DDSs and the associated strategies for ensuring targeted delivery and stimuli-responsiveness applied to CIDs are discussed extensively. The implementation of traditional routes of drug administration to maximize their therapeutic effects against CIDs is then summarized. Finally, perspectives on future DDSs against CIDs are presented.

논문정보

형식Review Paper
게재일2023년 10월 (BRIC 등록일 2023-11-03)
연구진국내(교신)+국외 연구진
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