한빛사논문
- 조회477
Hanjun Hwangbo*, SooJung Chae*, Wonjin Kim, Seoyul Jo, Geun Hyung Kim
Department of Precision Medicine, Sungkyunkwan University School of Medicine (SKKU-SOM) Suwon 16419, Republic of Korea
*The authors contributed equally.
Corresponding author: Prof. GeunHyung Kim
Abstract
The integration of tumor-on-a-chip technology with mini-tissues or organoids has emerged as a powerful approach in cancer research and drug development. This review provides an extensive examination of the diverse biofabrication methods employed to create mini-tissues, including 3D bioprinting, spheroids, microfluidic systems, and self-assembly techniques using cell-laden hydrogels. Furthermore, it explores various approaches for fabricating organ-on-a-chip platforms. This paper highlights the synergistic potential of combining these technologies to create tumor-on-a-chip models that mimic the complex tumor microenvironment and offer unique insights into cancer biology and therapeutic responses.
논문정보
- Review Paper
- 2023년 10월 (BRIC 등록일 2023-10-30)
- 국내 연구진
- 바이오·의료융합 > 바이오·의료융합 기타
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