전수지 (University of California, Riverside)

한빛사논문

조회204

전수지Su-Ji Jeon

University of California, Riverside

Small, Oct 15 2023, | https://doi.org/10.1002/smll.202304588 Targeted Delivery of Sucrose-Coated Nanocarriers with Chemical Cargoes to the Plant Vasculature Enhances Long-Distance Translocation

Su-Ji Jeon ¹, Yilin Zhang ², Christopher Castillo ¹, Valeria Nava ², Kurt Ristroph ², Benjamin Therrien ², Leticia Meza ¹, Gregory V Lowry ², Juan Pablo Giraldo ¹

¹Department of Botany and Plant Sciences, University of California, Riverside, CA, 92521, USA.

²Department of Civil and Environmental Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.

CORRESPONDING AUTHOR : Juan Pablo Giraldo

Abstract

Current practices for delivering agrochemicals are inefficient, with only a fraction reaching the intended targets in plants. The surfaces of nanocarriers are functionalized with sucrose, enabling rapid and efficient foliar delivery into the plant phloem, a vascular tissue that transports sugars, signaling molecules, and agrochemicals through the whole plant. The chemical affinity of sucrose molecules to sugar membrane transporters on the phloem cells enhances the uptake of sucrose-coated quantum dots (sucQD) and biocompatible carbon dots with β-cyclodextrin molecular baskets (suc-β-CD) that can carry a wide range of agrochemicals. The QD and CD fluorescence emission properties allowed detection and monitoring of rapid translocation (<40 min) in the vasculature of wheat leaves by confocal and epifluorescence microscopy. The suc-β-CDs more than doubled the delivery of chemical cargoes into the leaf vascular tissue. Inductively coupled plasma mass spectrometry (ICP-MS) analysis showed that the fraction of sucQDs loaded into the phloem and transported to roots is over 6.8 times higher than unmodified QDs. The sucrose coating of nanoparticles approach enables unprecedented targeted delivery to roots with ≈70% of phloem-loaded nanoparticles delivered to roots. The use of plant biorecognition molecules mediated delivery provides an efficient approach for guiding nanocarriers containing agrochemicals to the plant vasculature and whole plants.

논문정보

형식Research article
게재일2023년 10월 (BRIC 등록일 2023-10-23)
연구진국외 연구진
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