한빛사논문
- 조회336
Sunmin Woo, a Lewis Marquez,b William J. Crandall, b Caitlin J. Risener b and Cassandra L. Quave*ac
aCenter for the Study of Human Health, Emory University, USA
bMolecular and Systems Pharmacology Program, Laney Graduate School, Emory University, USA
cDepartment of Dermatology, Emory University School of Medicine, USA
*Corresponding author : Cassandra L. Quave
Abstract
Covering: 2018 to 2022Antimicrobial resistance (AMR) poses a significant global health threat. There is a rising demand for innovative drug scaffolds and new targets to combat multidrug-resistant bacteria. Before the advent of antibiotics, infections were treated with plants chosen from traditional medicine practices. Of Earth's 374 000 plant species, approximately 9% have been used medicinally, but most species remain to be investigated. This review illuminates discoveries of antimicrobial natural products from plants covering 2018 to 2022. It highlights plant-derived natural products with antibacterial, antivirulence, and antibiofilm activity documented in lab studies. Additionally, this review examines the development of novel derivatives from well-studied parent natural products, as natural product derivatives have often served as scaffolds for anti-infective agents.
논문정보
- Review Paper
- 2023년 07월 (BRIC 등록일 2023-08-01)
- 국외 연구진
- 의약학 > 약학
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