한빛사논문
- 조회397
Kijun Park a, Seunghoi Kim b, Yejin Jo a, Jae Park a, Inwoo Kim c, Sooyoung Hwang a, Yeontaek Lee a, So Yeon Kim c, Jungmok Seo a
aSchool of Electronic and Electronic Engineering, Yonsei University, Seoul, 03722, Republic of Korea
bCenter for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technologies, Seoul, 02792, Republic of Korea
cCenter for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technologies, Seoul, 02792, Republic of Korea
Corresponding author : Jungmok Seo
Abstract
Implantable biomedical devices require an anti-biofouling, mechanically robust, low friction surface for a prolonged lifespan and improved performance. However, there exist no methods that could provide uniform and effective coatings for medical devices with complex shapes and materials to prevent immune-related side effects and thrombosis when they encounter biological tissues. Here, we report a lubricant skin (L-skin), a coating method based on the application of thin layers of bio-adhesive and lubricant-swellable perfluoropolymer that impart anti-biofouling, frictionless, robust, and heat-mediated self-healing properties. We demonstrate biocompatible, mechanically robust, and sterilization-safe L-skin in applications of bioprinting, microfluidics, catheter, and long and narrow medical tubing. We envision that diverse applications of L-skin improve device longevity, as well as anti-biofouling attributes in biomedical devices with complex shapes and material compositions.
논문정보
- Research article
- 2023년 07월 (BRIC 등록일 2023-06-09)
- 국내 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
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