한빛사논문
- 조회334
Ju Seung Lee 1, Jiwoong Choi 2, Gha Yeon Park 3,4, Seung Ji Kang 1, Jae-Hun Yang 1, Youngkyu Lee 1, Myunghwan Choi 3,4, Kwangmeyung Kim 5, Tae-Il Kim 1
1School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.
2Medicinal Materials Research Center, Biomedical Research Division, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
3School of Biological Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
4Institute of Molecular Biology and Genetics, Seoul National University, Seoul, 08826, Republic of Korea.
5College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Republic of Korea.
CORRESPONDING AUTHORS : Kwangmeyung Kim, Tae-Il Kim
Abstract
The development of fabrication technologies and appearance of new materials has resulted in dramatic increase in the performance of electronic devices, while the overall size has decreased. Recent electronic devices made of micro/nano-size components show high efficiency and outstanding performance with compact size, but these devices have revealed several fatal problems. In particular, the isolated heat that is generated by numerous components concentrated in a limited small area at high density, such as bio-integrated devices, is an issue that needs to be urgently addressed, because it is closely related to the performance and lifetime of electronic devices. To solve these problems, the microscale light emitting diode (µLED)-based neural probe is introduced on an injectable heat dissipation guide. The heat dissipation guide is made of boron nitride (BN) nanomaterials with high thermal conductivity. The heat management noticeably improves the optical output performance of the µLEDs, in which BN effectively dissipates heat, and allows enhanced lighting from the LEDs to be transmitted through brain tissue without thermal damage. Moreover, it shows remarkable improvement in the therapeutic effect of photodynamic therapy of mouse cancer cells.
논문정보
- Research article
- 2023년 04월 (BRIC 등록일 2023-06-02)
- 국내 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
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