한빛사논문
- 조회365
Paritosh Patel a, Aditya Nandi b, Suresh K. Verma b,c, Neha Kaushik d, Mrutyunjay Suar b, Eun Ha Choi a, Nagendra Kumar Kaushik a
aPlasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, 01897 Seoul, South Korea
bSchool of Biotechnology, KIIT University, Bhubaneswar 751024, Odisha, India
cCondensed Matter Theory Group, Materials Theory Division, Department of Physics and Astronomy, Uppsala University, Box 516, SE-751 20 Uppsala, Sweden
dDepartment of Biotechnology, College of Engineering, The University of Suwon, 18323 Hwaseong, Republic of Korea
Corresponding authors: Eun Ha Choi, Nagendra Kumar Kaushik
Abstract
Emerging bio-contaminants such as viruses have affected health and environment settings of every country. Viruses are the minuscule entities resulting in severe contagious diseases like SARS, MERS, Ebola, and avian influenza. Recent epidemic like the SARS-CoV-2, the virus has undergone mutations strengthen them and allowing to escape from the remedies. Comprehensive knowledge of viruses is essential for the development of targeted therapeutic and vaccination treatments. Animal models mimicking human biology like non-human primates, rats, mice, and rabbits offer competitive advantage to assess risk of viral infections, chemical toxins, nanoparticles, and microbes. However, their economic maintenance has always been an issue. Furthermore, the redundancy of experimental results due to aforementioned aspects is also in examine. Hence, exploration for the alternative animal models is crucial for risk assessments. The current review examines zebrafish traits and explores the possibilities to monitor emerging bio-contaminants. Additionally, a comprehensive picture of the bio contaminant and virus particle invasion and abatement mechanisms in zebrafish and human cells is presented. Moreover, a zebrafish model to investigate the emerging viruses such as coronaviridae and poxviridae has been suggested.
논문정보
- Review Paper
- 2023년 05월 (BRIC 등록일 2023-05-08)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 바이오소재
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