한빛사논문
- 조회213
성균관대학교
Hamna Haq Chouhdry1,2, Dong Hyun Lee3, Atanu Bag3,4 & Nae-Eung Lee1,2,3,4,5,6,7
1SKKU Advanced Institute of Nano Technology (SAINT), Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
2Department of Nano Science and Technology, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
3School of Advanced Materials Science & Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
4Research Centre for Advanced Materials Technology, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
5Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
6Institute of Quantum Biophysics (IQB), Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
7Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
Corresponding authors : Correspondence to Atanu Bag or Nae-Eung Lee.
Abstract
The human olfactory system comprises olfactory receptor neurons, projection neurons, and interneurons that perform remarkably sophisticated functions, including sensing, filtration, memorization, and forgetting of chemical stimuli for perception. Developing an artificial olfactory system that can mimic these functions has proved to be challenging. Herein, inspired by the neuronal network inside the glomerulus of the olfactory bulb, we present an artificial chemosensory neuronal synapse that can sense chemical stimuli and mimic the functions of excitatory and inhibitory neurotransmitter release in the synapses between olfactory receptor neurons, projection neurons, and interneurons. The proposed device is based on a flexible organic electrochemical transistor gated by the potential generated by the interaction of gas molecules with ions in a chemoreceptive ionogel. The combined use of a chemoreceptive ionogel and an organic semiconductor channel allows for a long retentive memory in response to chemical stimuli. Long-term memorization of the excitatory chemical stimulus can be also erased by applying an inhibitory electrical stimulus due to ion dynamics in the chemoresponsive ionogel gate electrolyte. Applying a simple device design, we were able to mimic the excitatory and inhibitory synaptic functions of chemical synapses in the olfactory system, which can further advance the development of artificial neuronal systems for biomimetic chemosensory applications.
논문정보
- Research article
- 2023년 02월 (BRIC 등록일 2023-04-14)
- 국내 연구진
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