한빛사논문
- 조회578
Jina Son a, Seo Hyun Lim a, Yu Jin Kim a, Hye Jin Lim a, Ji Yeon Lee a, Seona Jeong a, Chulhwan Park b, Si Jae Park a
aDepartment of Chemical Engineering and Materials Science, Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul 03760, Republic of Korea
bDepartment of Chemical Engineering, Kwangwoon University, Seoul 01897, Republic of Korea
Corresponding author: Si Jae Park
Abstract
Preventing catastrophic climate events warrants prompt action to delay global warming, which threatens health and food security. In this context, waste management using engineered microbes has emerged as a long-term eco-friendly solution for addressing the global climate crisis and transitioning to clean energy. Notably, Pseudomonas putida can valorize industry-derived synthetic wastes including plastics, oils, food, and agricultural waste into products of interest, and it has been extensively explored for establishing a fully circular bioeconomy through the conversion of waste into bio-based products, including platform chemicals (e.g., cis,cis-muconic and adipic acid) and biopolymers (e.g., medium-chain length polyhydroxyalkanoate). However, the efficiency of waste pretreatment technologies, capability of microbial cell factories, and practicability of synthetic biology tools remain low, posing a challenge to the industrial application of P. putida. The present review discusses the state-of-the-art, challenges, and future prospects for divergent biosynthesis of versatile products from waste-derived feedstocks using P. putida.
논문정보
- Review Paper
- 2023년 03월 (BRIC 등록일 2023-03-15)
- 국내 연구진
- 생명과학 > 생물공학
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