한빛사논문
- 조회349
Inae Lee a,b,1, Eunyoung Jeon a,1, Joonseok Lee a,b,c
aDepartment of Chemistry, Hanyang University, Seoul, 04763, South Korea
bResearch Institute for Convergence of Basic Sciences, Hanyang University, 222 Wangsimni-Ro, Seongdong-Gu, Seoul, 04763, South Korea
cResearch Institute for Natural Sciences, Hanyang University, Seoul, 04763, South Korea
1I.L. and E.J. contributed equally to this work.
Corresponding author: Joonseok Lee
Abstract
As the recent coronavirus disease (COVID-19) pandemic and several severe illnesses such as Middle East respiratory syndrome coronavirus (MERS-CoV), Influenza A virus (IAV) flu, and severe acute respiratory syndrome (SARS) have been found to be airborne, the importance of monitoring bioaerosols for the control and prevention of airborne epidemic diseases outbreaks is increasing. However, current aerosol collection and detection technologies may be limited to on-field use for real-time monitoring because of the relatively low concentrations of targeted bioaerosols in air samples. Microfluidic devices have been used as lab-on-a-chip platforms and exhibit outstanding capabilities in airborne particulate collection, sample processing, and target molecule analysis, thereby highlighting their potential for on-site bioaerosol monitoring. This review discusses the measurement of airborne microorganisms from air samples, including sources and transmission of bioaerosols, sampling strategies, and analytical methodologies. Recent advancements in microfluidic platforms have focused on bioaerosol sample preparation strategies, such as sorting, concentrating, and extracting, as well as rapid and field-deployable detection methods for analytes on microfluidic chips. Furthermore, we discuss an integrated platform for on-site bioaerosol analyses. We believe that our review significantly contributes to the literature as it assists in bridging the knowledge gaps in bioaerosol monitoring using microfluidic platforms.
논문정보
- Review Paper
- 2023년 01월 (BRIC 등록일 2023-02-24)
- 국내 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
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