한빛사논문
Hong-Bo Cheng 1, Xiaoqiao Cao 1, Shuchun Zhang 1, Keyue Zhang 1, Yang Cheng 1, Jiaqi Wang 1, Jing Zhao 1, Liming Zhou 2, Xing-Jie Liang 3,4, Juyoung Yoon 5
1State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, College of Materials Science and Engineering, Beijing University of Chemical Technology, 15 North Third Ring Road, Beijing, 100029, P. R. China.
2Henan Provincial Key Laboratory of Surface and Interface Science, School of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002, China.
3CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, No. 11, First North Road, Zhongguancun, Beijing, 100190, China.
4School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 510260, P. R. China.
5Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Korea.
CORRESPONDING AUTHOR : Hong-Bo Cheng, Xing-Jie Liang, Juyoung Yoon
Abstract
The outline of the review is as follows. In Section 2, the synthesis and regulatory strategies for BODIPY are summarized, and inspiring cutting-edge work in post-functionalization strategies is highlighted. Section 3 gives a brief overview of assembly model of BODIPY. In this section, we introduce BODIPY as a promising building block for the formation of single- and multi-component self-assembled systems, including nanostructures suitable for aqueous environments, thereby showing the great development potential of supramolecular assembly in biomedicine applications. Section 4 describes the frontier progress of BODIPY in biomedical applications. This section reviews examples of the frontiers of biomedical applications of BODIPY-containing smart materials. It mainly involves the application of materials based on BODIPY building blocks and their assemblies in fluorescence bioimaging, PAI, disease treatment including PDT, PTT and immunotherapy. In Section 5, not only the current status of the BODIPY family in the biomedical field but also the challenges worth considering are summarized. At the same time, it also provides insights into the future development prospects of biomedically applicable BODIPY.
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