한빛사논문
- 조회231
Naline Bellier # 1, Phornsawat Baipaywad # 1 2, Naeun Ryu 1, Jae Young Lee 3, Hansoo Park 4
1School of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
2Biomedical Engineering Institute, Chiang Mai University, Chiang Mai, 50200, Thailand.
3School of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
4School of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
#Contributed equally.
Corresponding authors : Correspondence to Jae Young Lee or Hansoo Park.
Abstract
Recently, nanocarriers, including micelles, polymers, carbon-based materials, liposomes, and other substances, have been developed for efficient delivery of drugs, nucleotides, and biomolecules. This review focuses on graphene oxide (GO) and reduced graphene oxide (rGO) as active components in nanocarriers, because their chemical structures and easy functionalization can be valuable assets for in vitro and in vivo delivery. Herein, we describe the preparation, structure, and functionalization of GO and rGO. Additionally, their important properties to function as nanocarriers are presented, including their molecular interactions with various compounds, near-infrared light adsorption, and biocompatibility. Subsequently, their mechanisms and the most appealing examples of their delivery applications are summarized. Overall, GO- and rGO-based nanocomposites show great promise as multipurpose nanocarriers owing to their various potential applications in drug and gene delivery, phototherapy, bioimaging, biosensing, tissue engineering, and as antibacterial agents.
논문정보
- Review Paper
- 2022년 11월 (BRIC 등록일 2023-01-27)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 바이오소재
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