Moonjeong Bok 1, Zhi-Jun Zhao 2, Soon Hyoung Hwang 1, Junseong Ahn 1, Jiwoo Ko 1, Joo-Yun Jung 1, Jihye Lee 1, Sohee Jeon 1, Jun-Ho Jeong 1
1Nano-Convergence Manufacturing Systems Research Division, Korea Institute of Machinery and Materials, Daejeon 34103, South Korea.
2Institute of Smart City and Intelligent Transportation, Southwest Jiaotong University, Pidu District, Chengdu, Sichuan 610097, China.
Corresponding Author: Jun-Ho Jeong
Biocompatible adhesive films are important for many applications (e.g., wearable devices, implantable devices, and attachable sensors). In particular, achieving self-adhesion on one side of a film with biocompatible materials is a compelling goal in adhesion science. Herein, we report a simple and easy manufacturing process using water-soluble hyaluronic acid (HA) that allows adhesiveness on only one side using binary polymer mixtures based on a phase-separation strategy with an elastomer. HA influx allows for the entangled polymer chains of the elastomer to spontaneously deform, permitting tunable mechanical elasticity, conformability, and adhesion. The proposed adhesive film enables the transfer of nanopatterning and the attachment of various surfaces without the use of additional chemicals. In addition, the film can be used for measuring epidermal biopotential and for skin fixation of drug devices. Therefore, the developed facile asymmetric adhesion can block the interferences of other materials on the unnecessary adhesion side, providing considerable potential for the development of functional, multifunctional, and smart bioadhesives.