한빛사논문
- 조회343
Yeongjun Lee # 1 2, Yuxin Liu # 3 4, Dae-Gyo Seo # 1, Jin Young Oh 2, Yeongin Kim 5, Jinxing Li 2, Jiheong Kang 2, Jaemin Kim 2, Jaewan Mun 2, Amir M Foudeh 2, Zhenan Bao 6, Tae-Woo Lee 7 8 9
1Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea.
2Department of Chemical Engineering, Stanford University, Stanford, CA, USA.
3Department of Bioengineering, Stanford University, Stanford, CA, USA.
4Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
5Department of Electrical Engineering, Stanford University, Stanford, CA, USA.
6Department of Chemical Engineering, Stanford University, Stanford, CA, USA.
7Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea.
8School of Chemical and Biological Engineering, Seoul National University, Seoul, Republic of Korea.
9Institute of Engineering Research, Research Institute of Advanced Materials, Soft Foundry, Seoul National University, Seoul, Republic of Korea.
#Contributed equally.
These authors contributed equally: Yeongjun Lee, Yuxin Liu, Dae-Gyo Seo.
Corresponding authors: Correspondence to Zhenan Bao or Tae-Woo Lee.
Abstract
By relaying neural signals from the motor cortex to muscles, devices for neurorehabilitation can enhance the movement of limbs in which nerves have been damaged as a consequence of injuries affecting the spinal cord or the lower motor neurons. However, conventional neuroprosthetic devices are rigid and power-hungry. Here we report a stretchable neuromorphic implant that restores coordinated and smooth motions in the legs of mice with neurological motor disorders, enabling the animals to kick a ball, walk or run. The neuromorphic implant acts as an artificial efferent nerve by generating electrophysiological signals from excitatory post-synaptic signals and by providing proprioceptive feedback. The device operates at low power (~1/150 that of a typical microprocessor system), and consists of hydrogel electrodes connected to a stretchable transistor incorporating an organic semiconducting nanowire (acting as an artificial synapse), connected via an ion gel to an artificial proprioceptor incorporating a carbon nanotube strain sensor (acting as an artificial muscle spindle). Stretchable electronics with proprioceptive feedback may inspire the further development of advanced neuromorphic devices for neurorehabilitation.
논문정보
- Research article
- 2022년 08월 (BRIC 등록일 2022-12-19)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
댓글 작성 로그인
팝업 닫기관련 링크
연구자 키워드
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
해당논문 저자보기
