한빛사논문
Makoto Araki 1, Seung-Jung Park 2, Harold L Dauerman 3, Shiro Uemura 4, Jung-Sun Kim 5, Carlo Di Mario 6, Thomas W Johnson 7, Giulio Guagliumi 8, Adnan Kastrati 9, Michael Joner 10, Niels Ramsing Holm 11, Fernando Alfonso 12, William Wijns 13, Tom Adriaenssens 14, Holger Nef 15, Gilles Rioufol 16, Nicolas Amabile 17, Geraud Souteyrand 18, Nicolas Meneveau 19, Edouard Gerbaud 20, Maksymilian P Opolski 21, Nieves Gonzalo 22, Guillermo J Tearney 1, Brett Bouma 1, Aaron D Aguirre 1, Gary S Mintz 23, Gregg W Stone 24, Christos V Bourantas 25, Lorenz Räber 26, Sebastiano Gili 27, Kyoichi Mizuno 28, Shigeki Kimura 29, Toshiro Shinke 30, Myeong-Ki Hong 5, Yangsoo Jang 5, Jin Man Cho 31, Bryan P Yan 32, Italo Porto 33, Giampaolo Niccoli 34, Rocco A Montone 35, Vikas Thondapu 1, Michail I Papafaklis 36, Lampros K Michalis 36, Harmony Reynolds 37, Jacqueline Saw 38, Peter Libby 39, Giora Weisz 40, Mario Iannaccone 41, Tommaso Gori 42, Konstantinos Toutouzas 43, Taishi Yonetsu 44, Yoshiyasu Minami 45, Masamichi Takano 46, O Christopher Raffel 47, Osamu Kurihara 46, Tsunenari Soeda 48, Tomoyo Sugiyama 49, Hyung Oh Kim 31, Tetsumin Lee 50, Takumi Higuma 51, Akihiro Nakajima 1, Erika Yamamoto 52, Krzysztof L Bryniarski 53, Luca Di Vito 54, Rocco Vergallo 35, Francesco Fracassi 35, Michele Russo 35, Lena M Seegers 1, Iris McNulty 1, Sangjoon Park 55, Marc Feldman 56, Javier Escaned 57, Francesco Prati 58, Eloisa Arbustini 59, Fausto J Pinto 60, Ron Waksman 61, Hector M Garcia-Garcia 61, Akiko Maehara 23, Ziad Ali 23, Aloke V Finn 62, Renu Virmani 62, Annapoorna S Kini 63, Joost Daemen 64, Teruyoshi Kume 4, Kiyoshi Hibi 65, Atsushi Tanaka 66, Takashi Akasaka 66, Takashi Kubo 66, Satoshi Yasuda 67, Kevin Croce 39, Juan F Granada 23, Amir Lerman 68, Abhiram Prasad 68, Evelyn Regar 69, Yoshihiko Saito 70, Mullasari Ajit Sankardas 71, Vijayakumar Subban 71, Neil J Weissman 72, Yundai Chen 73, Bo Yu 74, Stephen J Nicholls 75, Peter Barlis 76, Nick E J West 77, Armin Arbab-Zadeh 78, Jong Chul Ye 55, Jouke Dijkstra 79, Hang Lee 1, Jagat Narula 24, Filippo Crea 35, Sunao Nakamura 80, Tsunekazu Kakuta 49, James Fujimoto 81, Valentin Fuster 24, Ik-Kyung Jang 82 83*
1Massachusetts General Hospital, Boston, MA, USA.
2Asan Medical Center, Seoul, South Korea.
3University of Vermont, Burlington, VT, USA.
4Kawasaki Medical School, Okayama, Japan.
5Yonsei University College of Medicine, Seoul, South Korea.
6Careggi University Hospital, Florence, Italy.
7University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
8Ospedale Papa Giovanni XXIII, Bergamo, Italy.
9Technische Universität München and Munich Heart Alliance, Munich, Germany.
10German Heart Center, Munich, Germany.
11Aarhus University Hospital, Skejby, Denmark.
12Hospital Universitario La Princesa, Madrid, Spain.
13National University of Ireland Galway and Saolta University Healthcare Group, Galway, Ireland.
14University Hospitals Leuven, Leuven, Belgium.
15University of Giessen, Giessen, Germany.
16Hospices Civils de Lyon and Claude Bernard University, Lyon, France.
17Institut Mutualiste Montsouris, Paris, France.
18University Hospital of Clermont Ferrand, Clermont-Ferrand, France.
19University Hospital Jean Minjoz, Besançon, France.
20University Hospital of Bordeaux, Pessac, France.
21National Institute of Cardiology, Warsaw, Poland.
22Hospital Clinico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
23Cardiovascular Research Foundation, New York, NY, USA.
24Icahn School of Medicine at Mount Sinai, New York, NY, USA.
25Barts Health NHS Trust, University College London and Queen Mary University London, London, UK.
26Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
27Centro Cardiologico Monzino, IRCCS, Milan, Italy.
28Mitsukoshi Health and Welfare Foundation, Tokyo, Japan.
29Yokohama Minami Kyosai Hospital, Kanagawa, Japan.
30Showa University Hospital, Tokyo, Japan.
31Kyung Hee University, Seoul, South Korea.
32Chinese University of Hong Kong, Hong Kong, Hong Kong.
33University of Genoa, Genoa, Italy, San Martino Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy.
34University of Parma, Parma University Hospital, Parma, Italy.
35Catholic University of the Sacred Heart, Rome, Italy.
36University Hospital of Ioannina, Ioannina, Greece.
37New York University Grossman School of Medicine, New York, NY, USA.
38Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
39Brigham and Women's Hospital, Boston, MA, USA.
40New York Presbyterian Hospital, Columbia University Medical Center and Cardiovascular Research Foundation, New York, NY, USA.
41Ospedale San Giovanni Bosco, Turin, Italy.
42Universitäts medizin Mainz and DZHK Rhein-Main, Mainz, Germany.
43National and Kapodistrian University of Athens, Athens, Greece.
44Tokyo Medical and Dental University, Tokyo, Japan.
45Kitasato University School of Medicine, Kanagawa, Japan.
46Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan.
47The Prince Charles Hospital, Chermside, Queensland, Australia.
48Nara Medical University, Nara, Japan.
49Tsuchiura Kyodo General Hospital, Ibaraki, Japan.
50Japanese Red Cross Musashino Hospital, Tokyo, Japan.
51Kawasaki Municipal Tama Hospital, St. Marianna University School of Medicine, Kanagawa, Japan.
52Kyoto University Graduate School of Medicine, Kyoto, Japan.
53Jagiellonian University Medical College, Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, Krakow, Poland.
54Mazzoni Hospital, Ascoli Piceno, Italy.
55Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
56University of Texas Health, San Antonio, TX, USA.
57Hospital Clínico San Carlos, Madrid, Spain.
58UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy.
59IRCCS Foundation University Hospital Policlinico San Matteo, Pavia, Italy.
60Santa Maria University Hospital, CHULN Center of Cardiology of the University of Lisbon, Lisbon School of Medicine, Lisbon Academic Medical Center, Lisbon, Portugal.
61MedStar Washington Hospital Center, Washington, DC, USA.
62CV Path Institute, Gaithersburg, MD, USA.
63Mount Sinai Hospital, New York, NY, USA.
64Erasmus University Medical Centre, Rotterdam, Netherlands.
65Yokohama City University Medical Center, Kanagawa, Japan.
66Wakayama Medical University, Wakayama, Japan.
67Tohoku University Graduate School of Medicine, Sendai, Japan.
68Mayo Clinic, Rochester, MN, USA.
69University Hospital Zürich, Zürich, Switzerland.
70Gifu University Graduate School of Medicine, Gifu, Japan.
71Madras Medical Mission, Chennai, India.
72MedStar Health Research Institute, Washington, DC, USA.
73Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
74The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
75Monash University, Melbourne, Victoria, Australia.
76University of Melbourne, Melbourne, Victoria, Australia.
77Royal Papworth Hospital, Cambridge, UK.
78Johns Hopkins University, Baltimore, MD, USA.
79Leiden University Medical Centre, Leiden, Netherlands.
80New Tokyo Hospital, Chiba, Japan.
81Massachusetts Institute of Technology, Cambridge, MA, USA.
82Massachusetts General Hospital, Boston, MA, USA.
83Kyung Hee University, Seoul, South Korea.
*Corresponding author.
Abstract
Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in the management of patients with acute coronary syndromes. Detection by OCT of healed coronary plaque has been important in our understanding of the mechanisms involved in plaque destabilization and healing with the rapid progression of atherosclerosis. Accurate detection by OCT of sequelae from percutaneous coronary interventions that might be missed by angiography could improve clinical outcomes. In addition, OCT has become an essential diagnostic modality for myocardial infarction with non-obstructive coronary arteries. Insight into neoatherosclerosis from OCT could improve our understanding of the mechanisms of very late stent thrombosis. The appropriate use of OCT depends on accurate interpretation and understanding of the clinical significance of OCT findings. In this Review, we summarize the state of the art in cardiac OCT and facilitate the uniform use of this modality in coronary atherosclerosis. Contributions have been made by clinicians and investigators worldwide with extensive experience in OCT, with the aim that this document will serve as a standard reference for future research and clinical application.
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