한빛사논문
Hyungseok Yong a,1, Sungwon Jung b,1, Deokjae Heo a, Woojin Choi b, Jihoon Chung a, Seongeun Cho b, Patrick Hwang c, Hyeonhui Song c, Won-gun Koh b, Wonhwa Lee d,*, Sangmin Lee a,*, Jinkee Hong b,*
a School of Mechanical Engineering, Chung-Ang University, 84 Heukseuk-ro, Dongjack-gu, Seoul 06974, Republic of Korea b School of Chemical & Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea c Barun Gonghak Co., Ltd., 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea d Aging Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea
* Corresponding authors.
1 These authors contributed equally to this work.
Abstract
Unlike chemotherapy, physical stimulation is body-friendly method which does not introduce foreign substances into the human body; however, since the use of the separate power source is dominant, there are forced restrictions. Herein, we report an innovative electrical stimulation method using the body-mediated energy loss conversion (BELC) system. The BELC system is a structure-concept-device that concentrates a local electric field in the desired area by utilizing energy loss from body movement as a power source; and the human body as an energy transfer medium. Concentrated electrical energy in the BELC system induces a low-frequency electric field that vitalizes the cell functions locally. Results from 3D simulation, designed cloth (patch, sleeve, athleisure) containing the BELC system and ex-vivo experiments demonstrate the electric field concentration through the human body without additional electrical components. Vitalization of cells and skins by the BELC system was inspected via in-vitro and in-vivo model; and insignificant side-effects of energy transfer pass-through mouse body were investigated.
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