한빛사논문
- 조회377
Jia Mei Hong1†, Hyeyoung Lee1†, Nishanth V. Menon2, Chwee Teck Lim2,3,4, Luke P. Lee5,6,7,8,9,10*, Catherine W. M. Ong1,3*‡
1Infectious Diseases Translational Research Programme, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore. 2Department of Biomedical Engineering, National University of Singapore, Singapore 117583, Singapore. 3Institute for Health Innovation & Technology (iHealthtech), National University of Singapore, Singapore 117599, Singapore. 4Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore. 5Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA. 6Berkeley Sensor and Actuator Center, University of California, Berkeley, Berkeley, CA 94720-1764, USA. 7Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA 94720, USA. 8Biophysics Graduate Program, University of California, Berkeley, Berkeley, CA 94720, USA. 9Harvard Medical School, Brigham and Women's Hospital, Harvard Institute of Medicine, Harvard University, Boston, MA 02115, USA. 10Institute of Quantum Biophysics, Department of Biophysics, Sungkyunkwan University, Suwon, Korea.
*Corresponding author.
†These authors contributed equally to this work as co-first authors.
‡Present address: National University Health System, 1E Kent Ridge Road, Tower Block, 10th Floor, Singapore 119228, Singapore.
Abstract
Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs) facilitate early detection, immediate treatment, and reduced transmission of TB disease. This Review evaluates current diagnostic assays endorsed by the World Health Organization and identifies the gaps between existing conventional tests and the ideal POCT. We discuss the commercial development of new rapid tests and research studies on nonsputum-based diagnostic biomarkers from both pathogen and host. Last, we highlight advances in integrated microfluidics technology that may aid the development of new POCTs.
논문정보
- Review Paper
- 2022년 04월 (BRIC 등록일 2022-11-01)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
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