Canran Wang^1,2,3,4,#, Xing Jiang^5,#, Han-Jun Kim^1,2,6,#, Shiming Zhang^1,2,7, Xingwu Zhou^1,2,8, Yi Chen^1,2,9,10, Haonan Ling^1,2,11, Yumeng Xue¹², Zhaowei Chen^1,13, MoyuanQu^1,2,14, Li Ren^1,2,15,16, Jixiang Zhu^1,2,17,18, Alberto Libanori^1,2, Yangzhi Zhu⁶, Heemin Kang¹⁹, Samad Ahadian^1,2,6,20, Mehmet R. Dokmeci^1,2,6,20, Peyman Servati²¹, Ximin He³, Zhen Gu^{1,22,23,24,25,26}, Wujin Sun^1,2,6,27*, and Ali Khademhosseini^{1,2,6,20,26,28*}

1. Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA
2. Center for Minimally Invasive Therapeutics (C-MIT), California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA
3. Department of Materials Science and Engineering, University of California, Los Angeles, CA 90095, USA
4.Andrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA 91125, USA
5. School of Nursing, Nanjing University of Chinese Medicine, Nanjing 210023, China
6.Terasaki Institute for Biomedical Innovation, Los Angeles, CA 90064, USA
7. Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong, SAR, China
8. Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, United States
9. Bloomage Biotechnology Co., Ltd., Jinan, Shandong 250101, China
10. Bloomage Biotechnology Hainan Co.,Ltd., Haikou, Hainan 571152, China
11.Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, CA 90095, USA
12. State Key Laboratory of Solidification Processing, Center for Nano Energy Materials, School of Materials Science and Engineering, Northwestern Polytechnical University and Shaanxi Joint Laboratory of Graphene (NPU), Xi'an, 710072, China
13. MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou 350108, China
14. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine,Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China
15. Key Laboratory for Space Bioscience and Biotechnology, School of Life Science, NorthwesterN Ploytechnical University, Xi’an, Shanxi 710072, China
16. Research Centre of Microfluidic Chip for Health Care and Environmental Monitoring, Yangtze River Delta Research Institute of Northwestern Polytechnical University inTaicang, Suzhou, Jiangsu 215400, China
17. Department of Biomedical Engineering, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China
18. The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China
19. Department of Materials Science and Engineering, Korea University, Seoul 02841, Republic of Korea
20. Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
21. Flexible Electronics and Energy Lab (FEEL), Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
22. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
23. MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
24. Zhejiang Laboratory of Systems & Precision Medicine, Zhejiang University Medical Center, Hangzhou 311121, China
25. Jinhua Institute of Zhejiang University, Jinhua 321299, China
26. Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA90095, USA
27. Department of Biological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA
28. Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA

^#These authors contributed equally to this work
^*Correspondence