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Trends Biotechnol., Available online 16 October 2021 | https://doi.org/10.1016/j.tibtech.2021.09.008
Proximity labeling: an enzymatic tool for spatial biology
Chang-Ryul Choi1, Hyun-Woo Rhee1,2,*
1Department of Chemistry, Seoul National University, Seoul 08826, Korea
2School of Biological Sciences, Seoul National University, Seoul 08826, Korea
*Corresponding author.
Abstract
In this Forum, we highlight how cutting-edge, proximity-dependent, enzymatic labeling tools, aided by sequencing technology developments, have enabled the extraction of spatial information of proteomes, transcriptomes, genome organization, and cellular networks. We also discuss the potential applications of proximity labeling in the unexplored field of spatial biology in live systems.
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- Forum
- 2021년 10월 (BRIC 등록일 2021-10-25)
- 국내 연구진
- 생명과학 > 생화학
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