한빛사논문
- 조회998
Kwon-Hyeon Kim, Paul H. Dannenberg, Hao Yan, Sangyeon Cho, and Seok-Hyun Yun*
K.-H. Kim, P. H. Dannenberg, H. Yan, S. Cho, S.-H. Yun
Wellman Center for Photomedicine and Harvard Medical School, Massachusetts General Hospital, 65 Landsdowne Street, Cambridge, MA 02139, USA
P. H. Dannenberg, S.-H. Yun
Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, 65 Landsdowne Street, Cambridge, MA 02139, USA
*To whom correspondence should be addressed.
Abstract
Fluorescent microbeads are widely used for applications in life sciences and medical diagnosis. The spectral contrast and sharpness of photoluminescence are critical in the utilities of microbeads for imaging and multiplexing. Here, microbeads capable of generating single-peak laser emission with a sub-nanometer linewidth are demonstrated. The microbeads are made of quantum dots that are tightly packed and crosslinked via ligand exchange for high optical gain and refractive index as well as material stability. Bright single-mode lasing with no photobleaching is achieved with particle diameters as small as 1.5 µm in the air. Sub-nm lasing emission is maintained even inside high-index surroundings, such as organic solvents and biological tissues. Feasibility of intracellular tagging and multi-color imaging in vivo is demonstrated.
논문정보
- Research article
- 2021년 08월 (BRIC 등록일 2021-10-21)
- 국외 연구진
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