한빛사논문
- 조회543
Minseok Lee1, Sangwon Lee2,3, Jejung Kim4, Jeongsik Lim4, Jinho Lee2,3, Samer Masri5, Shaowen Bao6, Sunggu Yang2, Jong-Hyun Ahn4 and Sungchil Yang1
1Department of Neuroscience, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong. 2Department of Nanobioengineering, Incheon National University, Incheon 22012, Republic of Korea. 3gBrain Inc., Incheon 21984, Republic of Korea. 4School of Electrical & Electronic Engineering, Yonsei University, Seoul 03722, Republic of Korea. 5Neuroscience Graduate Program, University of Arizona, Tucson, AZ 85721, USA. 6Department of Physiology, University of Arizona, Tucson, AZ 85724, USA
These authors contributed equally: Minseok Lee, Sangwon Lee, Jejung Kim
Correspondence: Sunggu Yang or JongHyun Ahn or Sungchil Yang
Abstract
Cortical maps, which are indicative of cognitive status, are shaped by the organism’s experience. Previous mapping tools, such as penetrating electrodes and imaging techniques, are limited in their ability to be used to assess high-resolution brain maps largely owing to their invasiveness and poor spatiotemporal resolution, respectively. In this study, we developed a flexible graphene-based multichannel electrode array for electrocorticography (ECoG) recording, which enabled us to assess cortical maps in a time- and labor-efficient manner. The flexible electrode array, formed by chemical vapor deposition (CVD)-grown graphene, provided low impedance and electrical noise because a good interface between the graphene and brain tissue was created, which improved the detectability of neural signals. Furthermore, cortical map remodeling was induced upon electrical stimulation at the cortical surface through a subset of graphene spots. This result demonstrated the macroscale plasticity of cortical maps, suggesting perceptual enhancement via electrical rehabilitation at the cortical surface.
논문정보
- Research article
- 2021년 10월 (BRIC 등록일 2021-10-07)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 뇌인지과학
댓글 작성 로그인
팝업 닫기관련 링크
연구자 키워드
관련분야 연구자보기
관련분야 논문보기
