구.농수식품
- 조회304
상명대학교
Je-Won Yoo1, Hayoung Cho1, MinJeong Jeon1, Chang-Bum Jeong2, Jee-Hyun Jung3,4, Young-Mi Lee1,*
1Department of Biotechnology, College of Convergence Engineering, Sangmyung University, Seoul 03016, Republic of Korea
2Department of Marine Science, College of Natural Sciences, Incheon National University, Incheon 22012, Republic of Korea
3Risk Assessment Research Center, Korea Institute of Ocean Science and Technology, Geoje 53201, Republic of Korea
4Department of Ocean Science, Korea University of Science and Technology, Daejeon 34113, Republic of Korea
*Corresponding author
Abstract
Owing to the increasing usage of plastics, their debris is continuously deposited in marine environments, resulting in deleterious effects on aquatic organisms. Although it is known that microplastics disturb the cellular redox status, knowledge of molecular in marine cladocerans is still lacking. In the present study, we investigated the acute toxicity of different-sized polystyrene (PS) beads (0.05, 0.5, and 6-μm diameter), ingestion and egestion patterns, their distribution in the tissues, and their effects on the antioxidant systems in the brackish water flea Diaphanosoma celebensis. All different-sized PS beads showed no mortality at the concentrations used in this study. After 48 h of exposure to PS beads of different sizes, all microbeads were retained in the digestive tract, but the retention time varied according to the bead size. In particular, the group that was exposed to 0.05-μm beads showed widely distributed fluorescence (e.g., in the embryo, and probably in lipid droplets as well as the digestive tract). The transcriptional level and enzyme activities of antioxidants were modulated depending on the size of the PS beads, and lipid peroxidation was induced in groups exposed to 0.05 and 0.5-μm beads. These findings suggest that the size of PS beads is an important factor for cellular toxicity, and can induce size-dependent oxidative stress in this species. This study provides a better understanding of the molecular modes of action of microplastics in marine zooplankton.
논문정보
- Research article
- 2021년 03월 (BRIC 등록일 2021-10-22)
- 국내 연구진
- 구・농수식품
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