구.농수식품
- 조회657
Young H Cho1, Sang Y Lee1,2,&, Chang-Hyung Lee3, Jong-Hwan Park4, Yong S So5
1Department of Family Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
2Department of Medical Education, Pusan National University School of Medicine, Yangsan, Republic of Korea.
3Department of Rehabilitation Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
4Health Convergence Medicine Laboratory, Biomedical Research Institute, Pusan National University Hospital, Pusan, Republic of Korea.
5Department of Physical Education, Dong-A University, Pusan, Republic of Korea.
*Corresponding author
Abstract
Background
Studies suggest that Schisandra chinensis Baillon (Sc) may enhance muscle strength and mass because of its anti-inflammatory and antioxidant properties.
Objectives
We aimed to examine the effects and safety of consumption of Sc extract (SCe) for 12 wk on muscle strength and mass in older adults with relatively low muscle mass who do low-intensity exercise.
Methods
A randomized, double-blind, placebo-controlled trial was performed in adults >50 y of age. Fifty-four participants were randomly assigned into 2 groups and, for 12 wk, received either 1 g SCe/d or a placebo. All participants were required to walk for 30–60 min/d for >3 d/wk during the trial period. At baseline and at 4 and 12 wk after treatment, the participants were examined for knee extension strength using Biodex isokinetic dynamometers, handgrip strengths, and body composition, and blood tests were performed. The Euro-QoL-5D (EQ-5D) questionnaire and the FFQ were administered at baseline and at 12 wk after treatment. Physical activity was assessed using a self-recorded daily exercise log and an accelerometer during the study.
Results
SCe supplementation over 12 wk caused a higher increase in right knee extensor strength by 10.2 Nm (95% CI: 3.7, 16.8 Nm; P = 0.003) and left knee extensor strength by 6.7 Nm (95% CI: 0.3, 13.1 Nm; P = 0.041) than did the placebo. However, no differences were observed in the muscle mass, anti-inflammatory markers, antioxidative markers, and EQ-5D score between the groups. None of the participants experienced adverse events.
Conclusions
SCe supplementation may enhance skeletal muscle strength but not mass in older adults who perform low-intensity exercise. This trial was registered at clinicaltrials.gov as NCT03402308.
논문정보
- Research article
- 2021년 03월 (BRIC 등록일 2021-09-14)
- 국내 연구진
- 구・농수식품
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