한빛사논문
- 조회544
Seeun Ha1, Byungchang Jin1, Brooke Clemmensen1, Paul Park1, Sumaiya Mahboob2, Vadim Gladwill2, Farah Madhani Lovely3, Andres Gottfried-Blackmore4, Aida Habtezion4, Subhash Verma5, Seungil Ro1
1Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, USA
2Internal Medicine, University of Nevada School of Medicine, Reno, Nevada, USA
3Pulmonary and Critical Care Medicine, Renown Health, Reno, Nevada, USA
4Gastroenterology and Hepatology, Stanford University Department of Medicine, Stanford, California, USA
5Microbiology and Immunology, University of Nevada School of Medicine, Reno, Nevada, USA
SH and BJ contributed equally.
Correspondence to Dr Seungil Ro
Abstract
We read with great interest the recent publication by Lin et al, which reported diarrhoea as the most common GI symptom in patients with COVID-19. Diarrhoea as a symptom of COVID-19 has been commonly observed, but the cause remains unknown. We found 5-HT levels are markedly elevated in COVID-19-associated diarrhoea. Elevated 5-HT levels in diarrhoea are also correlated with increased IL-6. These data suggest increased 5-HT may contribute to diarrhoea and the severity of COVID-19.
논문정보
- Letter
- 2021년 01월 (BRIC 등록일 2021-01-08)
- 국외 연구진
- 의약학 > 분자세포의학
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