한빛사논문
- 조회970
Joshua A. Jackmana,*, Bo Kyeong Yoona, Lei Ouyangb, Nan Wangb, Abdul Rahim Ferhanc, Jaeyun Kima,*, Tetsuro Majimab,* and Nam-Joon Choc,*
aSchool of Chemical Engineering and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Republic of Korea
bSchool of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
cSchool of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore
J.A.J. and B.K.Y. contributed equally to this work.
*To whom correspondence should be addressed.
Abstract
The ongoing coronavirus disease 2019 (COVID‐19) pandemic highlights the importance of developing effective virus targeting strategies to treat and prevent viral infections. Since virus particles are nanoscale entities, nanomaterial design strategies are ideally suited to create advanced materials that can interact with and mimic virus particles. In this progress report, the latest advances in biomimetic nanomaterials are critically discussed for combating viral infections, including in the areas of nanomaterial‐enhanced viral replication inhibitors, biomimetic virus particle capture schemes, and nanoparticle vaccines. Particular focus is placed on nanomaterial design concepts and material innovations that can be readily developed to thwart future viral threats. Pertinent nanomaterial examples from the COVID‐19 situation are also covered along with discussion of human clinical trial efforts underway that might lead to next‐generation antiviral therapies and vaccines.
Keywords : antiviral, biomimetic, COVID-19, nanomaterials, therapy, vaccine, virus
논문정보
- Progress Report
- 2020년 11월 (BRIC 등록일 2020-11-10)
- 국내(교신)+국외 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
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