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인하대학교

Biosens. Bioelectron., Available online 19 September 2020, 112620 | https://doi.org/10.1016/j.bios.2020.112620 Electrically conducting polymers for bio-interfacing electronics: From neural and cardiac interfaces to bone and artificial tissue biomaterials

Seunghyeon Lee^a,b, Busra Ozlu^a,b, Taesik Eom^a,b, David C. Martin^c,*, Bong Sup Shim^a,b,*

^aDepartment of Chemical Engineering, Inha University 100 Inharo, Incheon, 22212, South Korea
^bProgram in Biomedical Science & Engineering, Inha University 100 Inharo, Incheon, 22212, South Korea
^cDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA

^*Corresponding author

Abstract

Conductive polymers (CPs) are gaining considerable attention as materials for implantable bioelectronics due to their unique features such as electronic-ionic hybrid conductivity, mechanical softness, ease of chemical modification, as well as moderate biocompatibility. CPs have been utilized for a wide range of applications including neural engineering, regenerative medicine, multi-functional sensors and actuators. This review focuses on CP materials design for use in bio-interfacing electronics including composites, conductive hydrogels, and electrochemical deposition. We start by elaborating on the fundamental materials characteristics of CPs, including bio-electrochemical charge-transfer mechanisms, and contrast them with naturally derived CPs. We then present recent critical examples of the bioelectronic and biomedical applications of CPs, including neural recording and stimulation, tissue regeneration, stretchable electronics, and mechanical actuation. We conclude with a perspective of the current material challenges of CPs in bio-interfacing electronics.

Keywords : Conductive polymers; Neural interfaces; Tissue regeneration; Bioelectronics; Implantable electronics

논문정보

형식Review Paper
게재일2020년 09월 (BRIC 등록일 2020-10-08)
연구진국내(교신)+국외 연구진
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