한빛사논문
- 조회1,445
Yera Choia,1, Emily Yunha Shina,1, and Sungshin Kima,b,c,2
aCenter for Neuroscience Imaging Research, Institute for Basic Science, 16419 Suwon, Republic of Korea; bSungkyunkwan University, 16419 Suwon, Republic of Korea; and cDepartment of Cognitive Sciences, Hanyang University, 04763 Seoul, Republic of Korea
1Y.C. and E.Y.S. contributed equally to this work.
2To whom correspondence may be addressed.
Abstract
Motor skill learning involves a complex process of generating novel movement patterns guided by evaluative feedback, such as a reward. Previous literature has suggested anteroposteriorly separated circuits in the striatum to be implicated in early goal-directed and later automatic stages of motor skill learning, respectively. However, the involvement of these circuits has not been well elucidated in human de novo motor skill learning, which requires learning arbitrary action–outcome associations and value-based action selection. To investigate this issue, we conducted a human functional MRI (fMRI) experiment in which participants learned to control a computer cursor by manipulating their right fingers. We discovered a double dissociation of fMRI activity in the anterior and posterior caudate nucleus, which was associated with performance in the early and late learning stages. Moreover, cognitive and sensorimotor cortico-caudate interactions predicted individual learning performance. Our results suggest parallel cortico-caudate networks operating in different stages of human de novo motor skill learning.
de novo motor skill learning, caudate nucleuss, patiotemporal dissociation, cortico-caudate interactions, fMRI
논문정보
TOP52020년 후보
- Research article
- 2020년 09월 (BRIC 등록일 2020-09-17)
- 국내 연구진
댓글 작성 로그인
팝업 닫기관련 링크
연구자 키워드
관련분야 연구자보기
관련분야 논문보기
