이보영 (성균관대학교) | 한빛사논문 > 한빛사

구.농수식품

조회975

성균관대학교

Aquat. Toxicol. , Volume 222, May 2020, 105462 | https://doi.org/10.1016/j.aquatox.2020.105462 The genome of the harpacticoid copepod Tigriopus japonicus: Potential for its use in marine molecular ecotoxicology

Abstract

Chang-Bum Jeong^a,b,#, Bo-Young Lee^a,#, Beom-Soon Choi^c, Min-Sub Kim^a, Jun Chul Park^a, Duck-Hyun Kim^a, Minghua Wang^d,e, Heum Gi Park^f, Jae-Seong Lee^a,*

^aDepartment of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea
^bDepartment of Marine Science, College of Natural Sciences, Incheon National University, Incheon 22012, South Korea
^cPhyzen Genomics Institute, Seongnam 13558, South Korea
^dState Key Laboratory of Marine Environmental Science, College of the Environment & Ecology, Xiamen University, Xiamen 361102, China
^eFujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, Xiamen University, Xiamen 361102, China
^fDepartment of Marine Resource Development, College of Life Sciences, Gangneung-Wonju National University, Gangneung 25457, South Korea

^#These authors equally contributed to this work.

^*Corresponding author

Abstract
The copepod Tigriopus japonicus has been widely used as an experimental species in the field of ecotoxicology. We have sequenced and assembled the whole genome of T. japonicus with comparative analysis of gene families that represent detoxification phases in two additional public genomes of Tigriopus spp., namely, T. californicus and T. kingsejongensis. The total length of the T. japonicus assembled genome was 196.6 Mb with an N50 value of 10.65 Mb and consisted of 339 scaffolds and 25,143 annotated genes. The detoxification gene families encoding cytochrome P450s (CYP450s), glutathione S-transferases (GSTs), and ATP-binding cassette (ABC) proteins in Tigriopus spp. have shown species-dependent diversity in several gene sets, suggesting that these genes have undergone a species-specific expansion to increase their fitness to different marine habitats and environmental pressures. Our study will provide a better understanding of the detoxification system in Tigriopus spp. and will contribute to various areas of research, including ecotoxicology.

Keywords
Copepod; Tigriopus; Genome; Detoxification; Marine invertebrate

논문정보

형식Research article
게재일2020년 05월 (BRIC 등록일 2020-05-08)
연구진국내(교신)+국외 연구진
분야 생명과학 > 분류/생태/환경생물학
구분구・농수식품

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