한빛사논문
Daeyeong Kima, Sang A Hanb,c, Jung Ho Kimc, Ju-Hyuck Leea,*, Sang-Woo Kimb,* and Seung-Wuk Leed,e,*
aDepartment of Energy Science and Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea
bSchool of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon 440-746, Republic of Korea
cInstitute for Superconducting and Electronic Materials, Australian Institute for Innovative Materials, University of Wollongong, Squires Way, North Wollongong, NSW 2500, Australia
dDepartment of Bioengineering, University of California, Berkeley, CA 94720, USA
eBiological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
D.K. and S.A.H. contributed equally to this work.
*To whom correspondence should be addressed.
Abstract
Biomolecular piezoelectric materials are considered a strong candidate material for biomedical applications due to their robust piezoelectricity, biocompatibility, and low dielectric property. The electric field has been found to affect tissue development and regeneration, and the piezoelectric properties of biological materials in the human body are known to provide electric fields by pressure. Therefore, great attention has been paid to the understanding of piezoelectricity in biological tissues and its building blocks. The aim herein is to describe the principle of piezoelectricity in biological materials from the very basic building blocks (i.e., amino acids, peptides, proteins, etc.) to highly organized tissues (i.e., bones, skin, etc.). Research progress on the piezoelectricity within various biological materials is summarized, including amino acids, peptides, proteins, and tissues. The mechanisms and origin of piezoelectricity within various biological materials are also covered.
Keywords :amino acids, peptides, piezoelectricity, proteins, tissues
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